Mesothelioma Doctors

Mesothelioma Medical Specialists:

In addition, several types of medical professionals may consider. "mesothelioma. When medical knowledge is consistent with this disease:

* Oncologists (cancer specialists)

* Breast (chest) surgeon.

* Pulmonologists (lung doctors)

* Chemical and / or radiation experts.

In mesothelioma medical advice can indeed team of experts. In addition to mesothelioma treatment methods are often made by United.
List medical mesothelioma.

Here mesothelioma mesothelioma cancer, with emphasis on medical doctors and other asbestos-caused diseases:-

Midwest / South:

W. Roy Smythe, MD

Temple, TX

Phone: 254-724-2595

David C. Rice, MD
Houston, TX
Phone: (713) 794-1477

Lary A. Robinson, MD
Tampa, FL
Phone: (813) 972-8412

Craig W. Stevens, MD, PhD
Tampa, FL
Phone: (813) 972-8424

David P. Mason, MD
Cleveland, OH
Phone: (216) 444-4053

Gregory P. Kalemkerian, MD
Ann Arbor, MI
Phone: (734) 936-5281

Brian W. Loggie, MD
Omaha, NE
Phone: (402) 280-4100

East Coast / Atlantic Seaboard:

Harvey Pass, MD
New York, NY
Phone: (212) 263-7417

Robert N. Taub, MD
New York, NY
Phone: (212) 305-4076

Valerie W. Rusch, FACS
New York, NY
Phone: (212) 639-5873

Mark J. Krasna, MD
Towson, MD
Phone: (410) 427-2220

David H. Harpole, Jr., MD
Durham, NC
Phone: (919) 668-8413

Raja M. Flores, MD
New York, NY
Phone: (212) 639-2806

Paul H. Sugarbaker, MD, FACS, FRCS
Washington, DC
Phone: (202) 877-3908

David J. Sugarbaker, MD
Boston, MA
Phone: (617) 732-6824

Lambros Zellos, MD, MPH
Boston, MA
Phone: (617) 525-9657

Daniel Sterman, MD
Philadelphia, PA
Phone: (215) 614-0984

Joseph S. Friedberg, MD
Philadelphia, PA
Phone: (215) 662-9195

David L. Bartlett, MD
Pittsburgh, PA
Phone: (412) 692-2852

Stephen C. Yang, MD
Baltimore, MD
Phone: (410) 614-3891

West / West Coast:

Eric Vallieres, MD
Seattle, WA
Phone: (206) 598-4477

Robert Cameron, MD
Los Angeles, CA
Phone: (310) 794-7333

David M. Jablons, MD
San Francisco, CA
Phone: (415) 885-3882

Claire F. Verschraegen, MD
Albuquerque, NM
Phone: (505) 272-4551

Mesothelioma Drugs

Mesothelioma Drugs used in chemotherapy:

Mesothelioma Drugs are used in chemotherapy. Some victims of asbestos cancer (disease) are too far or too weak to be treated with surgery or radiotherapy, chemotherapy is the only option.

Typical is the administration of chemotherapy drugs, every week or two, for a longer period of time. In the case of the disease, many doctors have experience with combinations of chemotherapy drugs, is trying to encourage the hope of response.
Mesothelioma drug use

FDA approval Drug:

In 2004, issued its first FDA approval of drug-disease - that is to say that the product is especially chemotherapy in the treatment of cancer. This is pemetrexed drug, also known by its brand name Alimta. It is usually used in combination with platinum compounds known as cisplatin. Both drugs attack the cancer cell growth and appears to work well together.

Other drugs used to treat Mesothelioma:

Mesothelioma medical drugs, in combination, which are dictated by the type of cancer location and stage of development. Other drugs used to treat the disease are:

Carboplatin
* Carboplatin, other platinum drugs damage cancer cells.

Vinorelbine
* Vinorelbine is used in the treatment of breast cancer and small cell lung. Was developed with the periwinkle plant, or "Vinci". The drug stops cancer cells from dividing into two cells, thereby increasing virulence.

Gemcitabine
* Gemcitabine can also be used with cisplatin. This drug is a family of medicines called anti-metabolites. Anti-metabolites used to replace cells during DNA replication, effectively helps prevent the spread of cancer cells.

Ranpirnase
* Ranpirnase (Onconase) can selectively attack malignant cells and inhibits the growth of proteins. Unique ability to separate the cells is still down the unwanted side effects and give hope for selective targeting to tumor cells.

Malignant Epithelioid Mesothelioma

Malignant Mesothelioma is a rare form of cancer. This occurs when cancer cells malignant pleural collect - the thin layer of tissue that lines the chest cavity and covers the lungs.

Various risk factors malignant mesothelioma:

Malignant mesothelioma is a disease in which malignant cancer cells can be found in the peritoneum thin layer of tissue that lines the abdomen and covers most organs in the abdomen called the peritoneum.

work or live in a country where the asbestos is inhaled or ingested, living with a person who works near asbestos and exposure to a virus .

The period between exposure to asbestos and the onset of symptoms is estimated at 20 to 50 years, which explains why most cases are diagnosed later in life.

Signs of malignant mesothelioma include shortness of breath, weight loss, abdominal swelling, pain in the chest, or swelling and pain in the abdomen.

Diagnosis of malignant mesothelioma:

Among the thousands of people diagnosed with malignant mesothelioma each year, the overwhelming majority are men. Malignant mesothelioma diagnosed by clinical examination, chest radiography, complete blood count (CBC), sedimentation rate, bronchoscopy, cytological examinations, such as biopsy or fine needle aspiration biopsy (FNA), thoracoscopy, thoracotomy or laparotomy.

Categories of esothelioma;

Mesothelioma bad news is divided into three categories or histological types including epithelioid mesothelioma, sarcomatoid mesothelioma and biphasic mesothelioma. Other types of malignant mesothelioma are divided into sub-types in each category. In many cases, patients with malignant mesothelioma will be more than one cell type.

Epithelioid mesothelioma is approximately 50% -70% of all cases of malignant mesothelioma. This is the most common type of cell, with a tubular form with a uniform single cell nucleus. Epithelioid cells are shaped cubes. Epithelioid Mesothelioma occurs in the mesothelium, a protective layer called the epithelium tissues surrounding certain organs such as lung and gastrointestinal tract.

Symptoms of this type of malignant mesothelioma include chest pain, fluid accumulation and pleural effusions, respiratory problems and anxiety. It is important to note that epithelioid mesothelioma is often confused with adenocarcinoma. It is recommended that persons diagnosed with adenocarcinoma require review by a medical institution and experience with mesothelioma.

Treatment options for malignant mesothelioma sarcomatoid mesothelioma and epithelioid malignant and malignant biphasic mesothelioma are the same. Some treatments can be used alone or in combination with each other.

Ill-treatment for mesothelioma will be divided into two broad categories. These include traditional mesothelioma treatments and new mesothelioma treatments.

Mesothelioma treatment:

The treatment of mesothelioma surgery, chemotherapy and radiotherapy or radiotherapy. In many cases, this approach is trimodality professional, which means a large number of treatments in combination with the best results for a better chance of long-term survival, and / or better quality of life.

Types of treatments:

Types of treatment vary depending on the stage of malignant mesothelioma. There are four phases.

Types of malignant mesothelioma surgery pleurectomy / decortication, pneumonectomy, thoracentesis, and the more radical surgery - extrapleural pneumonectomy. Pleurectomy / decortication removes part of the infected lungs and lining around the chest; pneumonectomy involves the removal of the entire lung, and thoracentesis is the type of surgery, where the drainage of excess fluid in the lungs with a needle .

This process helps with breathing and reduces the stress and pressure in the lungs. Pleurectomy / decortication and pneumonectomy were carried out primarily to relieve pain and rarely have implications for the survival rate of patients.

Extrapleural pneumonectomy :

Extrapleural pneumonectomy is usually done in the early stages of malignant mesothelioma. It is a complex process that involves the removal of all investment-related lung, heart and diaphragm. This will prevent investments from being infected by mesothelioma.

This process will be relatively healthy patients and in combination with chemotherapy and radiotherapy. This is usually a time to recover. While extrapleural pneumonectomy last the life of many years, often not a cure for one of three types of malignant mesothelioma.

Radiation treatments:

Radiation treatments for three types of malignant mesothelioma of two basic types: internal radiation therapy is also known as brachytherapy and external beam radiotherapy.

Radiation used to kill cancer cells and reduce the volume of manageable size. It relieves pain and reduces symptoms such as shortness of breath. Radiation, however, is not without consequences. To kill all the cancer cells important in May at the expense of the patient.

Chemotherapy:

Chemotherapy include different types of drugs against cancer or injected directly into the lungs or in pill form or intravenously. Chemotherapy medicines to prevent the growth of cancer cells in patients with malignant mesothelioma. Unfortunately, these drugs May damage normal healthy cells, but can cause unpleasant side effects ranging from nausea and hair loss in anemia and bleeding. In addition, chemotherapy is not very effective in the fight against three types of malignant mesothelioma, sarcomatoid mesothelioma in particular.

News Notes Malignant mesothelioma treatments;

News Notes Malignant mesothelioma treatments include therapy, immunotherapy, radiation intensity-modulated or IMRT, photodynamic therapy or PDT and development of new chemotherapy agents. New mesothelioma treatment, such as observed therapy, immunotherapy, photodynamic therapy or PDT, and offer new hope for physicians and patients with mesothelioma.

Doctors, scientists and researchers trying to develop these new treatments in the hope that it will be successful only if the traditional therapies have failed. Until now, these new treatments for mesothelioma have not measured with traditional methods, but it is now used in conjunction with traditional methods and is, of course, monitoring and evaluation.

New treatments of malignant mesothelioma:
In addition to malignant mesothelioma of finding new treatments such as therapy, immunotherapy, radiation intensity-modulated or IMRT, photodynamic therapy or PDT, and the development of new chemotherapy agents, has other "radical therapy for malignant epithelioid mesothelioma, such as therapeutic angiogenesis, antineoplaston treatment, mesothelioma clinical trials, treatment with interferon and interleukin, and radiofrequency ablation.

A variety of complementary and alternative therapies are also discussed mesothelioma include: products, special diets, homeopathic medicine, acupuncture, massage therapy, a high dose of Vitamin C, Laetrile (amygdalin, issued by fruit), medicine and the East.

Malignant Mesothelioma

Stages of malignant mesothelioma

Patients with stage I have a significantly better prognosis than those with more advanced stages. Given the relative rarity of this disease, based on accurate information being survival is limited. A proposed staging system is based on principles and thoracic surgery clinical data are shown below.

This is a change to the system proposed by Butchart et al elderly. Stadiums Other systems have been used, including the current system of international TNM staging are summarized by the International Mesothelioma Interest Group.

* Stage I: disease confined within the capsule of the parietal pleura (ie, ipsilateral pleura, lung, pericardium and diaphragm).

* Phase II: All of stage I with positive intrathoracic (N1 and N2) lymph nodes
.
* Stage III: local extension of disease to the following areas, for example, the chest wall or mediastinum, heart, or through the diaphragm or peritoneum, with or without extrathoracic or contralateral (N3) lymph node involvement
.
* Stage IV: Metastatic disease outside.

For the purposes of the debate on the treatment in this summary, the disease is classified as localized or advanced.

Localized malignant mesothelioma:
The first phase I.

Advanced malignant mesothelioma:
The II, III and IV phases.

Localized Malignant Mesothelioma:

Standard treatment options:

1. Solitary mesothelioma:
A surgical en bloc resection, including the structures to ensure continuous disease without wide margins. Sessile polypoid lesions have a treatment with surgical resection to ensure maximum potential for healing.

2. Intracavitary mesothelioma:

* Palliative surgery (ie decortication and pleurectomy), with or without postoperative radiotherapy.

* Extrapleural pneumonectomy.

* Palliative radiotherapy.

Advanced malignant mesothelioma

Standard treatment options:

1. Symptomatic treatment includes drainage of effusions, chest tube pleurodesis, or thoracoscopic pleurodesis. (see bulletin PDQ on Cardiopulmonary Syndromes for more information.)

2. Palliative surgical resection selected patients.

3. Palliative radiotherapy.

4. Single agent chemotherapy. Answers pieces already on with doxorubicin, epirubicin, mitomycin, cyclophosphamide, cisplatin, carboplatin and ifosfamide.

5. Combination chemotherapy (by clinical assessment). Information about ongoing clinical trials established nic site.

6. Multimodality clinic.

7. Intracavitary treatment. Administration intrapleural or intraperitoneal chemotherapy (eg cisplatin, mitomycin and cytarabine) has been reported to produce a transient reduction of the size of the temporary increase Hhmonim and control of spills of small clinical studies. Additional studies are needed to define the role of intracavitary therapy.

Many of the second phase of chemotherapy trials have condemn. the safety and efficacy of pemetrexed, the antifolate, and cisplatin chemotherapy, in patients with malignant mesothelioma naive that were not eligible for curative surgery was demonstrated in a randomized phase III trial.
Evidence Level :

This trial compared pemetrexed (500 mg/m2) and cisplatin (75 mg/m2 day 1) with only cisplatin (75 mg/m2 day 1 intravenously every 21 days). With a total of 456 patients registered for the trial, 226 patients received pemetrexed plus cisplatin, 222 patients received cisplatin alone, and 8 patients received no treatment. After 117 patients were registered, folic acid and vitamin B12 were added to reduce their toxic effects.

Folic acid (350-1,000 mg here) was administered daily from 1 to 3 weeks before the first dose chemotherapy and continuing until the day 1 to 3 weeks after treatment ended. A vitamin B12 injection (1000 mg intramuscularly) was administered 1 to 3 weeks before the first dose chemotherapy, and repeated approximately every 9 weeks until the treatment has ended.

Dexamethasone (4 mg) or equivalent corticosteroid was administered twice a day here for rash prophylaxis to all patients 1 day before, day and 1 day after each pemetrexed dose.

The analysis of all patients who were randomized and treated, the combination of cisplatin and pemetrexed was associated with statistically significant improvement in survival compared with cisplatin isolation, the mean survival was 12.1 versus 9.3 months, respectively (P = .020).

Hazard ratio of death of patients on pemetrexed and cisplatin arm compared with the control arm was 0.77. Average time of progression was more significant that pemetrexed and cisplatin arm (5.7 months versus 3.9 months, P = .001).

The advantage of the combination of arms was also shown the vitamin-supplemented subgroup. The Middle of survival were 13.3 and 10.0 months in the combination of cisplatin alone group, respectively (P = .051).

The main negative effects of pemetrexed plus cisplatin regime were myelosuppression, fatigue, nausea, and shortness of breath. Most of grade 3 and 4 were significantly reduce the negative effects of vitamin supplementation does not decrease the efficiency.

Asbestos Removal

The most important part of the use of asbestos and the possibility of exposure to asbestos have been suspended dropped. However, some old buildings still insulation and floor / ceiling tiles contain asbestos are. Demolition of old buildings to work with great interest while limiting exposure to asbestos should be taken.

Respiratory dust on the filter that is not released in asbestos removal must be sealed to the air and destroy the area should be used.

Occupational Safety and Health Administration (OSHA) construction workers involved in asbestos removal for the protection of buildings containing comprehensive guidelines were established.

In addition to previous assumptions about the floor tiles are generally contains asbestos. When remodeling, it does not interfere with the new floor, be placed on top of old ones to the bottom of this asbestos is recommended. For housing, some Web site information removal of asbestos exposure limit, describes the procedure. Appropriate preventive measures, taking home the fatal asbestos workers and to avoid exposure and to prevent future cases of mesothelioma asbestos.


Inhalation of asbestos can cause mesothelioma asbestos

Inhalation of asbestos dust, asbestos and lead, the primary means of mesothelioma is asbestos exposure. Asbestos fibers in human lungs so they can bypass the natural filtration device is small. Once we're in the most sensitive parts of the lungs, the fibers are embedded in lung tissue. Durability and strength of these fibers, asbestos fire retardants for the manufacture of components and building materials are attractive.

However, the asbestos fibers remain the same functionality for many years in the lung tissue destroyed by the body's natural defense mechanism embedded can not. In the lung tissue or pleural mesothelioma mesothelioma can lead. In addition, asbestos fibers, including the lungs as a result of Asbestosis occurs.

Pleural Mesothelioma Symptoms

Mesothelioma is asbestos-related malignancy (cancer), which is almost always fatal.Malignant from mesothelioma cells lining is pleural and peritoneal cavities and the pericardium and the Tunica vaginalis.

Pleural mesothelioma is the most common and accounts for 70% of all cases of mesothelioma and peritoneal mesothelioma forms, the remaining 30%. Affected pericardial mesothelioma and mesothelioma is Tunica vaginalis are rare. This is due to the fact that asbestos fibers, which are the main cause of mesothelioma, it is inhaled and the lungs are organs that are first exposed to asbestos.

Mesothelioma is of the occupational diseases, such as it is usually in people exposed to asbestos at work, although it can occur in people without a history of asbestos exposure. Asbestos has been involved in more than 80% -90% and mesothelioma cases. At present there is no definitive cure for mesothelioma. The predictions of peritoneal mesothelioma is worse than the peritoneal mesothelioma.

Signs and symptoms of pleural mesothelioma

Pleural mesothelioma is the most common form of mesothelioma accounts for 70% of all cases of mesothelioma. Pericardial mesothelioma constitutes a majority of the remaining 30% of the cases. So the signs and symptoms related to these two diseases are listed below pleural mesothelioma most common symptoms are:

* Chest pain
* Shortness of breath (difficulty breathing)

The above symptoms are usually parallel and are the first to start running. But in some individual cases only in my present difficulty breathing without chest pain.

* Some of the symptoms are late
* Hoarseness voice information
* Dysphagia (difficulty swallowing)

Late symptoms of the disease is usually means that at a later stage, and this is a bad sign. Symptoms of other less common are:

* Weight loss
* Sweating
* Thorax mass

These symptoms are not full, but they are encountered. Pleural mesothelioma may cause many other symptoms of the disease extent as the surrounding structures of the heart, great vessels in the chest.

Pleural Mesothelioma

Malignant pleural mesothelioma is the most common type of mesothelioma, which constitute over two thirds of all cases. Pleural mesothelioma affects the lining of the lungs and chest cavity known as the pleura.

The pleura is composed of the parietal and visceral pleura. The parietal pleura lines the chest wall and diaphragm visceral pleura lines the lungs. Fluid between these membranes allows them to slide against each other as the lungs expand and contract.


Asbestos fibers in their work the smaller passages of the lungs, then in the pleura. Once there, an unknown chemical reaction causes cancerous cell development. As the cells begin to divide abnormally, thickening of the pleura and trim the excess liquid collected in May

Pleural thickening gradually contracts the margin of maneuver, which causes shortness of breath, often the first symptom of pleural mesothelioma.

The fluid, once carefully measured to allow smooth movement between the lungs and other organs, now causes increased pressure, further impeding breathing. This excess fluid is often seen in X-rays, and is considered a pleural breath.

Pleural mesothelioma, like all types of mesothelioma can be difficult to diagnose or easily misdiagnosed. If you are aware before the exposure to asbestos, it is important to tell your doctor if symptoms mesothelioma can be properly identified.

If a diagnosis of pleural mesothelioma is serious, is not without options. A series of new and new mesothelioma treatments are available, as well as various clinical studies.

Mesothelioma gene therapy

Currently, new approaches to malignant mesothelioma treatments are being tested. Mesothelioma treatments are usually combined traditional and something new is being introduced. Examples: finds therapy.

Gene therapy is a procedure for the treatment of fatal diseases or disabilities, modifying the expression of a person in a therapeutic genes. The purpose and goal of therapy is research-based correction of the disease at the DNA level and to compensate for abnormal genes.

Replacement therapy is a judge transferred displacement, often a tumor suppressor gene, and replaces it with a copy of the Standard finds that cell growth and division. P53 notes, the most important and the judge changed in the treatment of cancer has proved to be a target for the replacement of the judge, and was able to prevent cell growth, prevention of angiogenesis is the development of a tumor blood supply, and promote apoptosis.

Knockout therapy is to find products oncogenes (a conclusion which could stimulate the formation of the tumor) in an effort to stop the decline and the growth of the cell.

Due to the increase of knowledge is therapy treatment of malignant mesothelioma cancer, their roles and functions, and administers and distribution systems, this therapy has a promising future.

He was a great success in the detection of malignant mesothelioma cancer in its early stages, and treatment options ounces Mesothelioma is a cancer comfirmed has greatly improved, but there are many more cancer, mesothelioma cancer, which is not included and healing can still struggling to cope effectively.

In recent years, scientists have learned a lot about how cancer cells differ from normal cells and in an effort to discover drugs, no doubt serious side effects of chemotherapy, have now discovered that drugs targeting tumor itself, while the body enough normal cells.

Asbestos-induced lung cancer

The average man in the United States have 12 chances of lung cancer, and the average woman 16. Asbestos workers, however, about seven times more likely to die from lung cancer than people in general.

Most of asbestos-induced lung cancer begins in the lining of the bronchi, which are the air tubes in the lungs. But lung cancer can also begin in other regions of the lung.

Although asbestos lung cancer usually develops slowly and May not appear until several years after exposure to asbestos, when this occurs, cancer cells can metastasize or spread to other parts body.

The two most common forms are lung cancer and small cell lung cancer non-small cell lung cancer. Exposure to asbestos can be a factor in the development of each type of lung cancer. Non-small cell lung cancer accounts for 85% to 90% of lung cancers.

Those early asbestos-induced lung cancer often have no symptoms. Then, the most common symptoms include a persistent cough, chest pain, often aggravated by deep breathing, coughing or laughing, hoarseness, weight loss and loss of appetite, blood or rust-colored sputum (spit or phlegm), the difficulty breathing or shortness of breath, susceptibility to bronchitis and pneumonia, and wheezing.

The methods used for diagnosis of asbestos lung cancer include imaging tests that produce X-rays, CT scans, MRI and PET. If the cancer is indicated, then the tissue samples used to confirm that the cancer and determine the type. Tests biopsies, phlegm tests and blood tests.

Non-small cell lung cancer can be treated by surgery, radiotherapy, chemotherapy and targeted therapy (therapy that uses drugs designed to specifically target cancer cells and to go beyond their ability to grow) .

The rare lung cancer small cell is usually treated with chemotherapy, sometimes in combination with radiation, lung cancer small cell is very rarely treated by surgery.

Forecasts for any form of lung cancer is poor. Nearly 60% of people diagnosed with lung cancer die within one year and nearly 75% die within two years.

Approximately 16% of people diagnosed with non-small cell lung cancer survive the disease for more than five years and only six percent of people diagnosed with lung cancer small cell survival over five years.

Mesothelioma-Lung Cancer From Asbestos

Asbestos-Mesothelioma:

Mesothelioma is a form of lung cancer that is almost always caused by asbestos and is most commonly found in the outer casing of the lungs called the mesothelium. Most people who develop mesothelioma cancer asbestos Fibers of this Agreement, or are exposed to asbestos dust while they are working. In the case of mesothelioma was found a man with no previous occupational exposure, the summized that may be caused by exposure to asbestos Fibers found in the clothes of a person, your home, work in an area where asbestos dust was found.

Diagnosing mesothelioma:

There are several reasons that make diagnosing mesothelioma at an early stage would be very difficult. Symptoms of mesothelioma latency period can be anywhere between 20 to 50 years after the initial contact with asbestos, which means the symptoms will show that the cancer is already in its advanced stages. If symptoms are present, the diagnosis is still not a fast process.

There are a number of diseases that reflect the symptoms, which have been found in mesothelioma patients and, therefore, that mesothelioma is often the last stop - usually without the patient of the possibility of previous exposure to asbestos.

Success of treatment depends on the stage of mesothelioma, a cancer is found. As it has been found that the majority of mesothelioma are not detected until an advanced stage, treatment of mesothelioma is often referred to as "failed." Studies show that when taken in either phase I or II, treatment of mesothelioma - usually a combination of radiation and chemotherapy - has been successful in extending the life of the patient for five years at a rate of 74.6% (Wikipedia).

There is also an alternative treatment, which can be used in conjunction with conventional treatment, which has been shown to reduce the possibility of mesothelioma found in one patient.

Risk of Asbestos:

Asbestos has been used for many years a large number of domestic and industrial products because of its various forms and uses. It is fireproof, and can also be used if the insulation so that it can become very popular during the industrial revolution. It is not known whether people were aware of the dangers of asbestos at the time, but in 1900 the risk of asbestos becomes increasingly apparent.

People who lived in mining towns and other lung problems in general, surveys show that asbestos workers were dying at a young age. Asbestos in an undisturbed state, seems to pose a threat. But now, if it is damaged or friable Fibers that can be ingested, which can lead to these or other health problems.

Although some of the companies were aware of the danger, they continued to work with asbestos-containing products, regardless of their staff. Such blatant injustice is the reason for the popularity of mesothelioma trial.

Mesothelioma Treatments

New clinical trials were introduced on a regular basis, there are different types of treatment used for mesothelioma. The treatment used depends on many factors, including the extent of disease, age and medical history of patients and the location and type of mesothelioma.

The most common treatment is:

* Surgery, if the damaged area of tissue is removed. This may involve removing part of the organ, depending on the affected areas. * Radiation therapy, which involves the use of radiation treatment to kill cancer cells in the affected areas. * Chemotherapy, which is used for the body to use drugs to kill cancer cells.

Pneumonectomy:

Surgical procedure, which is known as pleural mesothelioma pneumonectomy can be used and consists of removing the diseased lungs. Extra-pleural pneumonectomy may be necessary, depending on the spread of the disease, and this may mean removing the parts of the diaphragm and lungs.

A high risk factor with this surgery, and the viability depends on the patient's general health, smoking habits and the extent of exposure to asbestos. A pleurectomy is another type of surgery available, and this part of the chest, abdominal lining and surrounding tissue may be removed.

Radiation treatment:

Radiation therapy, which offers the advantages of treating the affected area and exposing the cells to healthy tissue, is another drug used to treat mesothelioma. It's fast and frequently used method for several types of cancer, and mesothelioma.

It works through the placement of radioactive sources in affected areas, which will then give radiation to kill abnormal cells. The radiation will continue to be about a year, working to destroy the lungs. Radiotherapy may be used in conjunction with surgery, or if the patient is not good enough, that the operation may be used alone.
Chemotherapy treatment

Chemotherapy treatment may be administered in the form of pills or injected medication. The downside of chemotherapy is that the drug may be used include high toxicity, and therefore, patients may be quite ill. Side effects may include nausea, vomiting, hair loss, weight loss and physical fatigue. There are also a number of post-chemical drugs used to alleviate side effects of chemotherapy.

Chemotherapy drugs are not targeted towards a specific area, which was to make their way through the body and found in the damaged area. This means that they can affect the tissues and cells does not affect the disease, which may cause side effects again.
Palliative Therapies

Palliative treatments may also be used in patients with mesothelioma. These therapies to patients with draining excess water through the needle and suction. In order to prevent further fluid accumulation drugs may be fed through a tube for fluid drainage in the chest.

Often, a combination of treatments and a cocktail of drugs available to treat mesothelioma patients. Also, the type of treatment used depends on the age and physical health of the patient as well as how far the disease has spread and where it is located.

The above are some of the most common treatment being treated for mesothelioma, but they are not always effective mesothelioma patients. As a result, sufferers are mesothelioma treatment can be offered as part of a clinical trial of any of the traditional treatment.

New mesothelioma cancer treatment is constantly reviewed, medical-research, it is expected that effective treatment is discovered. These clinical trials allow the specialists to assess whether the treatment tested in May, one day, effective for general use in the treatment of mesothelioma.
Their clinical trials and we hope that patients who used to allow the guinea pigs, which enable them to become part of this important research and find a medicine that can help them and others the same situation.

Other asbestos-related cancer

While mesothelioma, the most common form of cancer associated with exposure to asbestos, the presence of asbestos fibers in the body can lead to a multitude of other very serious and life-threatening forms of cancer, including lung cancer (see below), gastrointestinal and cancer of the rectum cancer.

Please refer to the gastrointestinal tract and colorectal cancer for the information on these diseases.

According to the National Cancer Institute, the exposure to asbestos can also your risk of developing kidney, throat, esophagus and gallbladder cancer. In addition to cancer, asbestos is also associated with breast, ovarian and prostate cancer, as well as leukemia and lymphoma.

Lung Cancer

In addition to mesothelioma, lung cancer is the most common form of cancer associated with exposure to asbestos.

Another dangerous cancer caused by exposure to asbestos is a lung cancer, two types: lung cancer and lung cancer. The latter is the most common type, accounting for almost 80 percent of the cases. Detection of lung cancer is determined by the appearance of cancer cells under the microscope of the samples.

The symptoms of lung cancer include:

* Cough and chest pain
* Problems breathing or shortness of breath
* Changes in the size or color of sputum
* The presence of blood in the sputum
* Weight loss, fatigue and headache

As in the case of mesothelioma after exposure to asbestos, lung cancer symptoms appear many years after the first exposure to hazardous mineral. Anyone who suspects they have been exposed to asbestos and experienced symptoms of lung cancer, the advice of medical physician.

Diagnosis; Treatment and Cure:

In most cases, the patient is diagnosed with mesothelioma cancer has progressed to a stage of development later, because of delays associated with the disease.

Once the doctor suspects a patient has mesothelioma in May, one or more diagnostic tests are generally ordered. These tests include tests of medical imaging such as X-rays, CT scan and MRI and biopsy procedures that samples of fluids and tissues for the presence of cancer cells.

Diagnostic tests for the detection of cancer progression, and whether it has spread to other parts of the body.

Treatment and Cure:

Although it is not known at this stage of treatment for mesothelioma, many patients choose to get treatment for people living with cancer feel more comfortable.

Treatment options for mesothelioma can include:

* Surgery * Chemotherapy * Radiation * Terms of the trials of gene therapy and immunotherapy

Patients also elected in May as part of clinical trials, the results of a study to test the activity and the future treatment and medicines. Clinical trials are often studied mesothelioma patients who are eligible for the various studies and the desire to participate in efforts to help health workers in search of treatment of mesothelioma.

Causes:

Mesothelioma mainly caused by exposure to asbestos. Although the method of asbestos causes mesothelioma is currently under review, medical experts have some theories:

Asbestos Cancer Chart

Once asbestos is inhaled, it can lodge itself in your body causing the body's cells mutate and become cancerous.

* Asbestos causes irritation and inflammation of mesothelial cells, leading to irreversible scarring, and possibly cellular damage of cancer. * Asbestos fibers between the cells and disrupt the function of cellular structures that are necessary for normal cell division, causing cellular changes that lead to cancer. * Asbestos causes production of free radicals. These molecules damage DNA and cause mutations in cells become cancerous. * The presence of asbestos causes cells to produce onkobelkah. These molecules cause mesothelial cells to ignore the normal limit of cell division, and in May it lead to cancer development.

Mesothelioma:

During the last century, millions of people, without having been exposed to asbestos, a type of mineral fibers known to cause a variety of cancers.

Often called "asbestos cancer, mesothelioma is the most common form of cancer caused by exposure to asbestos.

Mesothelioma:

Mesothelioma, cancer is specifically focused on the mesothelial cells of the body.
Mesothelioma is a rare and aggressive cancer that develops in the mesothelial cells line many organs and body cavities.

The cancer generally attacks the thin lining of the lungs, abdomen or heart, known as the mesothelium?. Each year, approximately 2,000 to 3,000 new cases of malignant mesothelioma are diagnosed in the United States.
Types of mesothelioma

* Pleural Mesothelioma is the most common type of malignant mesothelioma, comprising about 75 percent of all cases of mesothelioma. This type develops in the lining of the lungs, called pleura. * Peritoneal Mesothelioma develops in the abdominal peritoneum, a layer covering the abdominal cavity and surrounds the abdominal organs. * Pericardial Mesothelioma develops in the pericardium, the membrane that surrounds the heart and provides protection and support for this organization. * Testicular mesothelioma, a rare form of mesothelioma develops in the lining that surrounds the testicle called the tunica vaginalis.

SYMPTOMS

Symptoms of mesothelioma usually occur 20 to 50 years after the first exposure to asbestos occurs. Symptoms of what, in the case of pleural mesothelioma, which often resemble less serious conditions such as influenza, can cause mesothelioma very difficult to diagnose. Symptoms include:

* Shortness of breath * Pain in the chest * Persistent cough * Fatigue * Night sweats or fever * Unexplained weight loss

Mesothelioma patients and their families often want to gather as much information as possible about mesothelioma after diagnosis. Asbestos.com offers a complete set which contains all information on this site and other materials to help patients and their families understand their diagnosis.

Asbestos Toxicity:

ATSDR Case Studies in Environmental Medicine (CSEM) is a series of self-instruction, the first educational materials designed to increase primary care provider's knowledge of hazardous substances into the environment and help the evaluation of patients potentially exposed to hazardous substances.

These documents are available online (on the interactive DVD and PDF) and include a patient education work and care to assist in the investigation of the clinical use.

CSEM cover a chemical topics as well as other areas of environmental medicine as a history of exposure, Pediatric Environmental Health, Environment and asthma triggers.

For more information and access to the ATSDR CSEM, please visit
http://www.atsdr.cdc.gov/HEC/CSEM/csem.html

smoking influences-Asbestos cancer

The factors that influence the risk of developing asbestos-related diseases:

May Several factors help determine how the impact of exposure to asbestos, including:

* Dose (how much a person exposed to asbestos).
* Duration (how long the person).
* The size, shape and chemical composition of asbestos fibers.
* The source of exposure.
* Risk factors as smoking and pre-existing lung disease.

While all forms of asbestos are considered hazardous, different types of asbestos fibers may be associated with different health risks.
For example, several studies suggest that amphibole forms of asbestos, can be more harmful than chrysotile, particularly for the risk of mesothelioma, as they tend to remain in the lungs for a longer period of time.

smoking influences:

Many studies have shown that the combination of smoking and asbestos exposure, especially dangerous. Smokers who are exposed to asbestos have a risk of developing lung cancer, which is more than the risks of asbestos and smoking added together.

It is obvious that stopping smoking reduces the risk of lung cancer among workers exposed to asbestos. Smoking combined with asbestos exposure does not appear to increase the risk of mesothelioma. However, people who have been exposed to asbestos in the workplace at any time during their life or the suspicion that they may be exposed should not smoke.

The asbestos-related diseases detection:

People who are exposed (or suspect they have been subjected to) asbestos fibers in the workplace, the environment or at home via a family contact should inform their doctor about their exposure history and whether they have symptoms. The symptoms of diseases associated with asbestos, may not appear for many decades after exposure.

This is especially important to consult a doctor if any of the following symptoms:

* Difficulty breathing, hoarseness or a whistle.
* Permanent cough that gets worse over time.
* Blood in the sputum (fluid) coughed from the lungs.
* Pain or tightening of the chest.
* Difficulty swallowing.
* Swelling of the face and neck.
* Loss of appetite.
* Weight loss.
* Fatigue or anemia.

A complete medical examination, including chest radiograph and pulmonary function tests in May be recommended. In a chest radiograph is now the most common tool used to detect asbestos-related diseases.

However, it is important to note that chest x-rays can not detect asbestos fibers in the lungs, but can help identify early signs of lung disease from exposure to asbestos.

Studies have shown that computed tomography (CT) (a series of pictures of areas inside the body taken from different angles, and drawings created by a computer linked to the X-ray machine) may be more effective than X-rays lung, the detection of asbestos-related lung abnormalities in humans that have been exposed to asbestos.

A lung biopsy, which detects microscopic asbestos fibers in pieces of lung tissue is removed surgically, is the most reliable test to confirm the presence of asbestos-related abnormalities. Bronchoscopy is less invasive than a biopsy test and found that asbestos fibers in materials washed from the lungs. Importantly, these tests can not determine the amount of asbestos a person may have been exposed to disease or development.

Asbestos fibers can also be detected in urine, faeces or mucus, but these tests are not reliable for determining the amount of asbestos in May be a present in an individual lung.

Asbestos-related diseases

Tthe health risks of exposure to asbestos:

People can be exposed to asbestos in the workplace, their communities and their homes. In the case of products containing asbestos is concerned, the tiny asbestos fibers released into the air.

When asbestos fibers to breathe, can get trapped in the lungs and remain there for long. Over time, these fibers can accumulate and cause inflammation and scarring that can affect breathing and lead to serious health problems.

Asbestos has been classified as a known human carcinogen (a substance that causes cancer) by the Ministry of Health and Human Services, EPA and the International Agency for Research on Cancer. Studies have shown that exposure to asbestos can lead to an increased risk of lung cancer and mesothelioma (a rare cancer of the thin membrane that line the chest and abdomen).

Although rare, mesothelioma is the most common cancer associated with exposure to asbestos. In addition to mesothelioma and lung cancer, some studies have shown links between exposure to asbestos and the gastrointestinal tract and colorectal cancer, as well as an increased risk of cancer of the throat, kidney, esophagus, gallbladder, and. However, the evidence inconclusive.

Asbestos effects can also increase the risk of asbestosis (inflammation that affects the state of the lungs, which can cause difficulty breathing, coughing, and permanent lung damage) and other nonmalignant lung and pleural disorders, including pleural plaques (changes in the membranes surrounding the lungs), pleural thickening, pleural fluid and benign (abnormal collections of fluid between layers of light fabrics and wall of the thoracic cavity). Although pleural plaques are not precursors of lung cancer, showed that people with pleural disease caused by exposure to asbestos may be at increased risk of lung cancer.


Risks of asbestos-related diseases:

Everyone is exposed to asbestos at some time in their lives. Low levels of asbestos in the air, water and soil. However, most people do not become ill from their exposure. People who become ill from asbestos are usually those who are exposed to it on a regular basis, most often in the workplace, where they work directly with the material or the environment through contact.

Since early 1940, millions of workers have been exposed to asbestos. Health risks of asbestos fibers have been recognized in workers exposed in shipbuilding, trade, asbestos mining and milling, manufacturing of asbestos textiles and other asbestos products, insulation work in construction and construction, as well as a number of other professions.

Demolition workers, dry removal, asbestos removal workers, firefighters, road workers can be exposed to asbestos fibers. Studies evaluating the risk of cancer faced by auto mechanics exposed to asbestos through brake repair is limited, but generally there is no safe level of asbestos exposure. As a result of government regulation and improvement of working methods, today's workers (those without previous exposure) may face risks lower than those in the past.

Persons involved in rescue, recovery and cleanup of the site on September 11, 2001 against the World Trade Center (WTC) in New York even at risk of developing asbestos-related diseases. Because asbestos was used in the construction of the North Tower of the World Trade Center when the building was attacked, hundreds of tons of asbestos were released into the atmosphere.

Those who are most at risk include firefighters, policemen, doctors, builders, and volunteers who worked in the rubble at the Ground Zero. Other risks are living in the vicinity of the WTC towers and those who attended schools nearby. These people must be followed to determine long-term health effects of exposure.

One study found that almost 70 percent of WTC rescue and recovery workers suffered new or worsening respiratory symptoms in the performance of work at the WTC site. The study describes the outcome of the WTC Worker and Volunteer Medical Screening Program, which was established to identify and describe opportunities for WTC-related health effects in the response. The study found that about 28 percent of tests were abnormal lung function tests, and 61 percent of people without health problems developed respiratory symptoms . However, it is important to note that these symptoms may be related to exposure to different components of asbestos waste.

While it is clear that health risks from exposure to asbestos increase with exposure to severe and longer exposure time, investigators have found asbestos-related diseases in individuals with only brief exposure. Typically, those who develop asbestos-related diseases show no signs of illness for a long time after their first exposure. This can take anywhere from 10 to 40 years or more symptoms of asbestos-related disease to appear.

There is some evidence that family members of workers exposed to asbestos at large are facing an increased risk of mesothelioma. This risk is believed to be the result of exposure to asbestos fibers in the house because of shoes, clothes, skin and hair of workers. To reduce these risks, federal law regulates work practices to limit asbestos was made this way.

Some workers may be required to shower and change clothes before they leave work, store their clothes in an area in the workplace, or wash their work clothes at home separately from other clothes.

Cases of mesothelioma were also observed in individuals without occupational exposure to asbestos, living near asbestos mines.

What is asbestos?

Asbestos is the name of a group of minerals that occur naturally in the environment as bundles of fibers that can be separated into thin, durable threads.
These fibers are resistant to heat, fire, and chemicals, and no driver. For these reasons, asbestos was widely used in many industries.

Chemically, the silicate minerals are asbestos-containing compound of silicon and oxygen atoms in its molecular structure.

Asbestos minerals are divided into two main groups: serpentine asbestos and amphibole asbestos. Containing serpentine minerals chrysotile asbestos, which has long, curly fibers, which can be woven. Chrysotile asbestos is a form that is widely used for commercial purposes. Amphibole asbestos minerals include actinolite, tremolite, anthophyllite, amosite and crocidolite. Amphibole asbestos straight, needle-type fibers, which are more fragile than serpentine asbestos and are more limited in their ability to produce.


How to use asbestos?

Asbestos was mined and used commercially in North America since late 1800. Increased their use during World War II . Since that time, asbestos was used in many industries. For example, in building and construction industry is used to strengthen cement and plastics, and insulation, roofing, fire protection and sound absorption.

In the shipbuilding industry used asbestos to insulate boilers, steam and hot water pipes. In the automotive industry uses asbestos in vehicle brake shoes and clutch pads. Asbestos was used in the ceiling and floor tiles, paints, coatings and adhesives, and plastics. Additionally, asbestos is found in the vermiculite, and garden products containing talc-containing crayons.

In late 1970, the U. S. Consumer Product Safety Commission (CPSC) banned the use of asbestos in the correction of compound wall and gas fireplaces because the asbestos fibers in these products can be released into the environment during use. In addition, manufacturers of electric hairdryers voluntarily stopped using asbestos in their products in 1979.

In 1989, the U. S. Environmental Protection Agency (EPA) banned all new uses of asbestos, but uses established prior to 1989 are still allowed. The EPA established regulations that require school systems to check the damage to the building of asbestos and to eliminate or reduce exposure to asbestos at the residents by removing the asbestos or encasing.

In June 2000, the CPSC concluded that the risk of childhood exposure to asbestos fibers in the smaller is very low. However, U.S. manufacturers these crayons agreed to eliminate talc from their products.

In August 2000, EPA conducted a series of tests to assess the risk to consumers from the adverse health effects associated with exposure to asbestos-contaminated vermiculite. The EPA concluded that exposure to asbestos in vermiculite products poses only a minimal health risk.

The EPA recommends that consumers reduce the risk associated with low occasional use of vermiculite in gardening activities by limiting the amount of dust in the use of vermiculite. In particular, the EPA suggests consumers use vermiculite outdoors or in well-ventilated place, keep moist vermiculite, and use it to avoid the dust of vermiculite in the house on clothing, but also uses pre-tension of land, which is less likely that the powder.

The rules described above, and other actions, coupled with widespread concerns about the health risks of asbestos, have resulted in a significant annual decline in U.S. the use of asbestos. Domestic consumption of asbestos amounted to about 803,000 tons in 1973, but fell to 2,400 metric tons in 2005.

Information about asbestos:

More information about asbestos is available on the OSHA Asbestos Web page. This page give more infomationhttp://www.osha.gov/SLTC/asbestos/index.html

OSHA’s national office can be contacted at:

Organization:	Office of Public Affairs Occupational Safety and Health Administration U.S. Department of Labor
Address:	Room N–3649 200 Constitution Avenue, NW. Washington, DC 20210
Telephone:	202–693–1999 1–800–321–6742 (1–800–321–OSHA)
TTY (for deaf or hard of hearing callers):	1–877–889–5627
Internet Web site:	http://www.osha.gov/as/opa/worker/index.html (workers’ page)

Mine workers can contact MSHA at:

Organization:	Office of Public Affairs Mine Safety and Health Administration U.S. Department of Labor
Address:	21st Floor 1100 Wilson Boulevard Arlington, VA 22209
Telephone:	202–693–9400 1–800–746–1553
Internet Web site:	http://www.msha.gov http://www.msha.gov/codeaphone/codeaphonenew.htm (National Hazard Reporting Page)

The National Institute for Occupational Safety and Health (NIOSH):

The part of the Centers for Disease Control and Prevention (CDC), is another Federal agency that is concerned with asbestos exposure in the workplace. NIOSH conducts asbestos-related research, evaluates work sites for possible health hazards, and makes exposure control recommendations.

NIOSH can be contacted at:

Organization:	Education and Information Division Information Resources Branch National Institute for Occupational Safety and Health
Address:	4676 Columbia Parkway Cincinnati, OH 45226
Telephone:	1–800–CDC–INFO (1–800–232–7636)
E-mail:	cdcinfo@cdc.gov
Internet Web site:	http://www.cdc.gov/niosh